Tissue Engineering: Oromaxillofacial reconstruction with platelet rich plasma (PRP)
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Molloy, et. al., (2003) address specific growth factors encountered in ligament and tendon healing. After reading about the factors found in superficial wounds, above, these should appear familiar, including: Platelet derived growth factor (PDGF)—produced shortly after tendon injury, stimulates production of other growth factors such as IGF-1, and is involved in the tissue remodeling phase of h...
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As a result, human growth factors have been widely studied and today there are clinical applications of several individual growth factors. Examples are a keratinocyte growth factor (Kepivance®, Sweden) for oral mucositis and platelet derived growth factor (Regranex, UK) for non-healing diabetic wounds. However, these exogenous growth factors, when applied outside their normal environment, may h...
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Tendon and ligament injuries (TLI) commonly occur in athletes and non-athletes alike, and remarkably debilitate patients' athletic and personal abilities. Current clinical treatments, such as reconstruction surgeries, do not adequately heal these injuries and often result in the formation of scar tissue that is prone to re-injury. Platelet-rich plasma (PRP) is a widely used alternative option t...
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Journal title
volume 1 issue None
pages 46- 48
publication date 2012-09
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